发明授权
- 专利标题: Psoriasin expression by breast epithelial cells
- 专利标题(中): 乳腺上皮细胞牛皮in素表达
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申请号: US12330342申请日: 2008-12-08
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公开(公告)号: US07776541B2公开(公告)日: 2010-08-17
- 发明人: Kornelia Polyak , Charlotta Enerback
- 申请人: Kornelia Polyak , Charlotta Enerback
- 申请人地址: US MA Boston
- 专利权人: Dana-Faber Cancer Institute, Inc.
- 当前专利权人: Dana-Faber Cancer Institute, Inc.
- 当前专利权人地址: US MA Boston
- 代理机构: Fish & Richardson P.C.
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS) These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS.
公开/授权文献
- US20090104618A1 Psoriasin Expression By Breast Epithelial Cells 公开/授权日:2009-04-23
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