发明授权
- 专利标题： Diagnosis of liver pathology through assessment of protein glycosylation
- 专利标题（中）： 通过评估蛋白质糖基化诊断肝脏病理学
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申请号： US11418598申请日： 2006-05-05
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公开(公告)号： US07776550B2公开(公告)日： 2010-08-17
- 发明人: Timothy M. Block , Mary Ann Comunale , Anand Mehta
- 申请人： Timothy M. Block , Mary Ann Comunale , Anand Mehta
- 申请人地址： US PA Philadelphia
- 专利权人： Philadelphia Health & Education Corporation
- 当前专利权人： Philadelphia Health & Education Corporation
- 当前专利权人地址： US PA Philadelphia
- 代理机构： Woodcock Washburn, LLP
- 主分类号： G01N33/53
- IPC分类号： G01N33/53
摘要：
Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting glycosylation, and more specifically fucosylation, on proteins in biological fluids, and comparing the detected glycosylation with reference values for the glycosylation of such proteins in healthy or disease states.
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