Invention Grant
US07776600B2 Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
有权
制备羟基磷灰石的方法及其在核酸递送中的用途
- Patent Title: Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
- Patent Title (中): 制备羟基磷灰石的方法及其在核酸递送中的用途
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Application No.: US11811992Application Date: 2007-06-13
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Publication No.: US07776600B2Publication Date: 2010-08-17
- Inventor: Prashant N. Kumta , Charles Sfeir , Jeffrey Owen Hollinger , Daiwon Chol , Lee Weiss , Phil Campbell
- Applicant: Prashant N. Kumta , Charles Sfeir , Jeffrey Owen Hollinger , Daiwon Chol , Lee Weiss , Phil Campbell
- Applicant Address: US PA Pittsburgh
- Assignee: Carnegie Mellon University
- Current Assignee: Carnegie Mellon University
- Current Assignee Address: US PA Pittsburgh
- Agency: K&L Gates LLP
- Main IPC: C01B25/12
- IPC: C01B25/12 ; A61L27/32 ; A61F2/00 ; A61K31/715 ; C12N15/00
Abstract:
Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite particles exhibit substantially superior cell transformation abilities as compared to known and commercially-available calcium phosphate kits. The nanocrystalline hydroxyapatite particles also find use in tissue engineering applications, for example bone and tooth engineering and repair applications.
Public/Granted literature
- US20080095820A1 Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids Public/Granted day:2008-04-24
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