发明授权
US07777004B2 Polypeptides comprising Fas activation and NKG2D-ligand domains
有权
包含Fas活化和NKG2D-配体结构域的多肽
- 专利标题: Polypeptides comprising Fas activation and NKG2D-ligand domains
- 专利标题(中): 包含Fas活化和NKG2D-配体结构域的多肽
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申请号: US11945747申请日: 2007-11-27
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公开(公告)号: US07777004B2公开(公告)日: 2010-08-17
- 发明人: Thomas E. Wagner , Yanzhang Wei
- 申请人: Thomas E. Wagner , Yanzhang Wei
- 申请人地址: US SC Greenville
- 专利权人: Thomas E. Wagner
- 当前专利权人: Thomas E. Wagner
- 当前专利权人地址: US SC Greenville
- 代理机构: Foley & Lardner LLP
- 主分类号: C07K5/10
- IPC分类号: C07K5/10
摘要:
The present invention is drawn to fusion proteins comprising (a) a ligand for an NK receptor and (b) a Fas activation domain, and to nucleic acids encoding such fusion proteins. The invention also includes methods of making and using such proteins and nucleic acids, including their use in preventing or treating cancer.
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