发明授权
- 专利标题： Benzimidazole derivatives: preparation and pharmaceutical applications
- 专利标题（中）： 苯并咪唑衍生物：制备和药物应用
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申请号： US10572958申请日： 2004-09-21
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公开(公告)号： US07781595B2公开(公告)日： 2010-08-24
- 发明人: DiZhong Chen , Hong Yan Song , Eric T. Sun , Niefang Yu , Yong Zou
- 申请人： DiZhong Chen , Hong Yan Song , Eric T. Sun , Niefang Yu , Yong Zou
- 申请人地址： SG Singapore Science Park II
- 专利权人： S*BIO Pte Ltd.
- 当前专利权人： S*BIO Pte Ltd.
- 当前专利权人地址： SG Singapore Science Park II
- 代理机构： Connolly Bove Lodge & Hutz LLP
- 国际申请： PCT/SG2004/000307 WO 20040921
- 国际公布： WO2005/028447 WO 20050331
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; A61K31/4439 ; A61K31/5377 ; C07D235/06 ; C07D401/06 ; C07D401/04 ; C07D413/06
摘要：
The present invention relates to hydroxamate compounds which are inhibitors of histone deacetylase. More particularly, the present invention relates to benzimidazole containing compounds and methods for their preparation. These compounds may be useful as medicaments for the treatment of proliferative disorders as well as other diseases involving, relating to or associated with dysregulation of histone deacetylase (HDAC).
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