发明授权
US07786146B2 Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
有权
5-氨基-4,6-二取代吲哚和5-氨基-4,6-二取代二氢吲哚的衍生物作为钾通道调节剂
- 专利标题： Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
- 专利标题（中）： 5-氨基-4,6-二取代吲哚和5-氨基-4,6-二取代二氢吲哚的衍生物作为钾通道调节剂
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申请号： US12189709申请日： 2008-08-11
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公开(公告)号： US07786146B2公开(公告)日： 2010-08-31
- 发明人: Jean-Michel Vernier , Huanming Chen , Jianlan Song
- 申请人： Jean-Michel Vernier , Huanming Chen , Jianlan Song
- 申请人地址： US CA Aliso Viejo
- 专利权人： Valeant Pharmaceuticals International
- 当前专利权人： Valeant Pharmaceuticals International
- 当前专利权人地址： US CA Aliso Viejo
- 代理机构： McDermott Will & Emery LLP
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/404 ; C07D401/06 ; C07D209/08
摘要：
This invention provides compounds of formula I where the dashed line represents an optional double bond; where R1 is phenyl, naphthyl, pyridyl, pyrimidyl, pyrrolyl, imidazolyl, pyrazyl, furyl, thienyl, oxazolyl, isoxazolyl, thiazolyl, or isothiazolyl, optionally substituted, and other substituents are defined herein. Such compounds are potassium channel modulators.