发明授权
- 专利标题： Metalloprotein inhibitors
- 专利标题（中）： 金属蛋白抑制剂
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申请号： US12503190申请日： 2009-07-15
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公开(公告)号： US07786316B2公开(公告)日： 2010-08-31
- 发明人: David T. Puerta , Seth M. Cohen , Jana A. Lewis
- 申请人： David T. Puerta , Seth M. Cohen , Jana A. Lewis
- 申请人地址： US CA Oakland
- 专利权人： The Regents of The University of California
- 当前专利权人： The Regents of The University of California
- 当前专利权人地址： US CA Oakland
- 代理机构： Schwegman, Lundberg & Woessner, P.A.
- 主分类号： C07D315/00
- IPC分类号： C07D315/00 ; C07D211/72
摘要：
The present invention relates to metalloprotein inhibitors comprising: a. an organic substituent and at least one zinc binding group (ZBG) covalently attached thereto; or b. a ZBG substituted by a side chain wherein the ZBG is of formula (I): wherein X is O or S and each R1, R2, R3, and R4 is individually hydrogen or an organic radical. The metalloprotein inhibitors are useful for preventing or treating a pathological disease, condition, or symptom that is associated with pathological metalloprotein activity and/or that is alleviated by inhibition of said activity.
公开/授权文献
- US20090286987A1 METALLOPROTEIN INHIBITORS 公开/授权日：2009-11-19
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