发明授权
- 专利标题: Method for applying lubricious coating to a polymeric article
- 专利标题(中): 将润滑涂层施加到聚合物制品上的方法
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申请号: US11076391申请日: 2005-03-09
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公开(公告)号: US07798639B2公开(公告)日: 2010-09-21
- 发明人: Lynn Cook Winterton , Yongxing Qiu , John Martin Lally , Manal M. Gabriel
- 申请人: Lynn Cook Winterton , Yongxing Qiu , John Martin Lally , Manal M. Gabriel
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Sheng-Hsin Hu; Jian Zhou
- 主分类号: G02C7/04
- IPC分类号: G02C7/04
摘要:
The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a lubricious coating including a capping layer of polyvinylpyrrolidone and/or at least one layer of a lubricious coating material and one layer of a polyionic material having charges opposite of the charges of the lubricious coating material. The lubricious coating on the medical device of the invention has increased lubricity, preferably characterized by an averaged CoF of about 3.0 or less, increased hydrophilicity characterized by an averaged contact angle of about 80 degree or less, and increased bacterial adhesion resistance, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having a lubricious coating thereon.
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