发明授权
US07799829B2 Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
失效
α-氨基酸氨基氧烷基氨基甲酸酯前药，合成和使用方法
- 专利标题： Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
- 专利标题（中）： α-氨基酸氨基氧烷基氨基甲酸酯前药，合成和使用方法
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申请号： US12416823申请日： 2009-04-01
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公开(公告)号： US07799829B2公开(公告)日： 2010-09-21
- 发明人: Xuedong Dai , Archana Gangakhedkar , Jia-Ning Xiang , Mark A Gallop
- 申请人： Xuedong Dai , Archana Gangakhedkar , Jia-Ning Xiang , Mark A Gallop
- 申请人地址： US CA Santa Clara
- 专利权人： XenoPort, Inc.
- 当前专利权人： XenoPort, Inc.
- 当前专利权人地址： US CA Santa Clara
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- 主分类号： A61K31/27
- IPC分类号： A61K31/27 ; C07C69/74
摘要：
Acyloxyalkyl carbamate prodrugs of α-amino acids, pharmaceutical compositions thereof, methods of making acyloxyalkyl carbamate prodrugs of α-amino acids and methods of using acyloxyalkyl carbamate prodrugs of α-amino acids, and pharmaceutical compositions thereof to treat a disease are disclosed. Acyloxyalkyl carbamate prodrugs of α-amino acids suitable for oral administration using sustained release dosage forms are also disclosed.
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