发明授权
US07807424B2 Methods of producing polyketide synthase mutants and compositions and uses thereof
有权
生产聚酮化合物合酶突变体的方法及其组合物和用途
- 专利标题： Methods of producing polyketide synthase mutants and compositions and uses thereof
- 专利标题（中）： 生产聚酮化合物合酶突变体的方法及其组合物和用途
-
申请号： US11876767申请日： 2007-10-22
-
公开(公告)号： US07807424B2公开(公告)日： 2010-10-05
- 发明人: Joseph P. Noel , Michael B. Austin , Marianne E. Bowman
- 申请人： Joseph P. Noel , Michael B. Austin , Marianne E. Bowman
- 申请人地址： US CA La Jolla
- 专利权人： The Salk Institute for Biological Studies
- 当前专利权人： The Salk Institute for Biological Studies
- 当前专利权人地址： US CA La Jolla
- 代理机构： Foley & Lardner LLP
- 代理商 Stephen E. Reiter
- 主分类号： C12P7/00
- IPC分类号： C12P7/00 ; C12N9/00
摘要：
The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic acid encoding such non-native polyketide synthases. Also disclosed are methods of producing mutant polyketide synthases, and methods of altering the activity and/or substrate specificity of putative polyketide synthases.
公开/授权文献
信息查询
