发明授权
- 专利标题： Methods and compositions for promoting attachment of cells of endothelial cell lineage to medical devices
- 专利标题（中）： 促进内皮细胞谱系细胞附着于医疗器械的方法和组合物
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申请号： US11649950申请日： 2007-01-05
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公开(公告)号： US07807624B2公开(公告)日： 2010-10-05
- 发明人: Daniel James Kenan , Paul Theodore Hamilton
- 申请人： Daniel James Kenan , Paul Theodore Hamilton
- 申请人地址： US NC Durham
- 专利权人： Affinergy, Inc.
- 当前专利权人： Affinergy, Inc.
- 当前专利权人地址： US NC Durham
- 代理商 Laura L. Kiefer
- 主分类号： C07K14/00
- IPC分类号： C07K14/00
摘要：
The present invention provides compositions and methods for an improved coating for medical devices. Provided is a biofunctional coating composition comprising at least one binding domain that has binding specificity for a surface material of a medical device, and at least one binding domain that has binding specificity for cells of endothelial cell lineage. Methods for coating a surface of a medical device, and for manufacturing of a medical device, comprise contacting the surface to be coated with the biofunctional coating material in an amount effective to form a coating, and may further comprise contacting the coated surface with cells of endothelial cell lineage to bind the cells of endothelial cell lineage to the coated surface.