发明授权
- 专利标题： Method of DNA sequencing using cleavable tags
- 专利标题（中）： 使用可裂解标签的DNA测序方法
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申请号： US10611409申请日： 2003-06-30
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公开(公告)号： US07816079B2公开(公告)日： 2010-10-19
- 发明人: Steven M. Fischer
- 申请人： Steven M. Fischer
- 申请人地址： US CA Santa Clara
- 专利权人： Agilent Technologies, Inc.
- 当前专利权人： Agilent Technologies, Inc.
- 当前专利权人地址： US CA Santa Clara
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C07H21/04
摘要：
The present invention provides novel systems for sequencing nucleic acid molecules using dNTPs that are 3′ end labeled with cleavable tags that block further extension and uniquely identify the bases to which they are attached. Removal of the tags liberates the 3′ ends of the extension products for further extension. In related embodiments, oligonucleotides containing sequence-related cleavable tags are employed in a ligation reaction to determine the sequence of a particular DNA sample.
公开/授权文献
- US20040033522A1 Method of DNA sequencing using cleavable tags 公开/授权日：2004-02-19
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