Invention Grant
US07816461B2 Block copolymers of polycarpolactone and poly (propylene funarate)
有权
聚内酯和聚(丙烯丙烯酸酯)的嵌段共聚物
- Patent Title: Block copolymers of polycarpolactone and poly (propylene funarate)
- Patent Title (中): 聚内酯和聚(丙烯丙烯酸酯)的嵌段共聚物
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Application No.: US11718962Application Date: 2005-11-18
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Publication No.: US07816461B2Publication Date: 2010-10-19
- Inventor: Shanfeng Wang , Michael J. Yaszemski , Lichun Lu , Bradford L. Currier
- Applicant: Shanfeng Wang , Michael J. Yaszemski , Lichun Lu , Bradford L. Currier
- International Application: PCT/US2005/042240 WO 20051118
- International Announcement: WO2006/055940 WO 20060526
- Main IPC: C08G63/91
- IPC: C08G63/91

Abstract:
Poly(propylene fumarate) is copolymerized with poly(caprolactone) diol to produce a block copolymer of poly(propylene fumarate) and poly(caprolactone). The biocompatible and bioresorbable block copolymer of poly(propylene fumarate) and poly(caprolactone) is useful in the fabrication of injectable and in-situ hardening scaffolds for tissue and/or skeletal reconstruction. The block copolymer can be crosslinked by redox or photo-initiation, with or without an additional crosslinker. Thus, the copolymer is both self-crosslinkable (without the use of any crosslinkers) and photocrosslinkable (in the presence of photons such as UV light).
Public/Granted literature
- US20080004368A1 Block Copolymers of Polycarpolactone and Poly (Propylene Funarate) Public/Granted day:2008-01-03
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