发明授权
- 专利标题： Inhibitors of kinases
- 专利标题（中）： 激酶抑制剂
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申请号： US12399429申请日： 2009-03-06
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公开(公告)号： US07820814B2公开(公告)日： 2010-10-26
- 发明人: Rajeev S. Bhide , Zhen-Wei Cai , Ligang Qian , Stephanie Barbosa , Louis Lombardo , Jeffrey Robl
- 申请人： Rajeev S. Bhide , Zhen-Wei Cai , Ligang Qian , Stephanie Barbosa , Louis Lombardo , Jeffrey Robl
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Elliott Korsen
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/53 ; A61P35/00
摘要：
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
公开/授权文献
- US20090170853A1 NOVEL INHIBITORS OF KINASES 公开/授权日：2009-07-02
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