A differential voltage mode driver and digital impedance calibration of same is provided. In one embodiment, the invention relates to a method of calibrating a differential driver circuit having a plurality of parallel driver stages, the differential driver circuit for driving a differential signal over a transmission line having an impedance, the method including determining an indication of an impedance of a plurality of parallel replica stages, wherein the plurality of parallel replica stages are replicas of the plurality of parallel driver stages, determining a number of the plurality of parallel replica stages to approximately match the measured impedance with the transmission line impedance, and activating a number of the plurality of parallel driver stages equal to the number of the plurality of parallel replica stages. In another embodiment, the invention relates to a differential voltage mode driver using at least one H-bridge driver stage.