Devices and methods to prevent airway collapse are disclosed. The device includes a mouthpiece featuring a positioning aid adjustable by inflation accomplished via a gas exchange port attachable to a source of pressure and a breathing tube. Inflation causes an asymmetric protrusion on the mouthpiece, preferably above the breathing tube so that the positioning aid fits into the roof of the mouth. Preferably, tongue movement is at least partially restricted. An additional device featuring a wearable battery operated compressor is further disclosed. A device in the form of a pacifier is disclosed as a preferred embodiment for use in young patients. Preferably, devices are supplied as articles of manufacture. Use of disclosed devices constitute methods of preventing collapse of the upper airway.