Invention Grant
- Patent Title: Exocrine gland tight junction-constituting protein jeap family
- Patent Title (中): 外分泌腺紧密连接蛋白家族
-
Application No.: US11522043Application Date: 2006-09-15
-
Publication No.: US07824676B2Publication Date: 2010-11-02
- Inventor: Miyuki Nishimura , Mayumi Asano , Yuichi Ono , Koji Morimoto , Masakazu Takeuchi , Yoko Inoue , Toshio Imai , Yoshimi Takai
- Applicant: Miyuki Nishimura , Mayumi Asano , Yuichi Ono , Koji Morimoto , Masakazu Takeuchi , Yoko Inoue , Toshio Imai , Yoshimi Takai
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- Main IPC: C07K16/18
- IPC: C07K16/18
Abstract:
A mouse cDNA library from gene fragments encoding proteins localizing at cell-cell junctions was screened by a technique visualizing localization of a protein to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.
Public/Granted literature
- US20080119641A1 Exocrine gland tight junction-constituting protein JEAP family Public/Granted day:2008-05-22
Information query
