Invention Grant
- Patent Title: Use of RIP in treating staphylococcus aureus infections
- Patent Title (中): 使用RIP治疗金黄色葡萄球菌感染
-
Application No.: US11395293Application Date: 2006-04-03
-
Publication No.: US07824691B2Publication Date: 2010-11-02
- Inventor: Naomi Balaban
- Applicant: Naomi Balaban
- Applicant Address: US MD Pikesville
- Assignee: Centegen, Inc.
- Current Assignee: Centegen, Inc.
- Current Assignee Address: US MD Pikesville
- Agency: DLA Piper LLP (US)
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K39/38 ; A61K39/00 ; A61K39/02 ; A61K39/085 ; A61K39/09 ; A61K39/08 ; A61K39/108 ; A61K39/07 ; A01N37/18 ; A61F13/00 ; A61F2/00 ; A61F6/06
Abstract:
The present composition combines an RNAIII-inhibiting peptide (RIP) with an antimicrobial peptide, such as a cathelicidin, that is capable of binding and neutralizing lipidic and polyanionic components of bacterial cell envelope. In another embodiment, the RIP is combined with an antibiotic, with or without an antimicrobial peptide. The present composition is advantageously used in a method of treatment of bacterial sepsis.
Public/Granted literature
- US20070071768A1 Use of RIP in treating staphylococcus aureus infections Public/Granted day:2007-03-29
Information query
IPC分类:
