Invention Grant
US07824853B2 Complex comprising at least two biospecific elements separated by a nucleic acid linker e.g. for identification of drug delivery candidates combinatorial library of such complexes
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复合物包含由核酸接头分离的至少两个生物特异性元件，例如 用于鉴定这种复合物的药物递送候选组合文库
- Patent Title: Complex comprising at least two biospecific elements separated by a nucleic acid linker e.g. for identification of drug delivery candidates combinatorial library of such complexes
- Patent Title (中): 复合物包含由核酸接头分离的至少两个生物特异性元件，例如 用于鉴定这种复合物的药物递送候选组合文库
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Application No.: US10505336Application Date: 2003-02-20
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Publication No.: US07824853B2Publication Date: 2010-11-02
- Inventor: Lars Branden , Edvard Smith
- Applicant: Lars Branden , Edvard Smith
- Applicant Address: SE Huddinge
- Assignee: Avaris AB
- Current Assignee: Avaris AB
- Current Assignee Address: SE Huddinge
- Agency: Young & Thompson
- Priority: SE0200531 20020222
- International Application: PCT/SE03/00277 WO 20030220
- International Announcement: WO03/070982 WO 20030828
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
A method for the production of a biomolecular complex having at least two functional elements each attached to a target molecule or area through binding elements, wherein each functional element is attached to a specific binding element, the binding element being a nucleotide sequence and the target molecule or area comprising the corresponding target sequence, and the target molecules or areas being separated from each other by a first linker or spacer and an optional second linker, the linkers being nucleic acid polymers having a pre-determined physical property.
Public/Granted literature
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