Invention Grant
US07824869B2 Use of biological photoreceptors as directly light-activated ion channels
有权
使用生物光感受器作为直接光活化离子通道
- Patent Title: Use of biological photoreceptors as directly light-activated ion channels
- Patent Title (中): 使用生物光感受器作为直接光活化离子通道
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Application No.: US10510628Application Date: 2003-04-11
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Publication No.: US07824869B2Publication Date: 2010-11-02
- Inventor: Peter Hegemann , Georg Nagel , Ernst Bamberg
- Applicant: Peter Hegemann , Georg Nagel , Ernst Bamberg
- Applicant Address: DE München
- Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
- Current Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften E.V.
- Current Assignee Address: DE München
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: DE10216005 20020411
- International Application: PCT/EP03/03799 WO 20030411
- International Announcement: WO03/084994 WO 20031016
- Main IPC: G01N33/00
- IPC: G01N33/00 ; C12Q1/02 ; C12N5/10 ; C12N1/19 ; C12N5/0793 ; C12N1/12
Abstract:
The invention is directed to a method for altering the ion conductivity of a membrane. The method comprises inserting a biological photoreceptor into the membrane. The biological photoreceptor is configured to act as a light-controlled ion channel. The photoreceptor used comprises an apoprotein and a light-sensitive polyene covalently bound to the apoprotein, wherein the polyene interacts with the apoprotein and functions as a light-sensitive gate.
Public/Granted literature
- US20050202398A1 Use of biological photoreceptors as directly light-activated ion channels Public/Granted day:2005-09-15
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