Invention Grant
- Patent Title: Method of transducing a protein into cells
- Patent Title (中): 将蛋白质转导入细胞的方法
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Application No.: US10306165Application Date: 2002-11-29
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Publication No.: US07824910B2Publication Date: 2010-11-02
- Inventor: Hidenori Yamada , Junichiro Futami , Hidetaka Nakanishi
- Applicant: Hidenori Yamada , Junichiro Futami , Hidetaka Nakanishi
- Applicant Address: JP Osaka-Shi, Osaka
- Assignee: Nippon Shokubai Co., Ltd.
- Current Assignee: Nippon Shokubai Co., Ltd.
- Current Assignee Address: JP Osaka-Shi, Osaka
- Agency: Connolly Bove Lodge & Hutz LLP
- Priority: JP2001-363967 20011129; JP2002-156197 20020529
- Main IPC: C12N5/00
- IPC: C12N5/00
Abstract:
The invention relates to a method for transducing a pharmaceutical protein or polypeptide that may be fluorescently labeled into a cell by forming a conjugate with a cationic polymer having cation values of more than 2 and no more than 250 and transducing the conjugate into the cell. The protein or peptide pharmaceutical agent is directly covalently bound to the cationic polymer or is covalently bound to the cationic polymer through a bifunctional crosslinking agent.
Public/Granted literature
- US20030138944A1 Method of transducing a protein into cells Public/Granted day:2003-07-24
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