Invention Grant
- Patent Title: Methods for the treatment of multiple myeloma
- Patent Title (中): 治疗多发性骨髓瘤的方法
-
Application No.: US11409927Application Date: 2006-04-24
-
Publication No.: US07825088B2Publication Date: 2010-11-02
- Inventor: Ulrich H. von Andrian , Irina Mazo , Jean-Marc Gauguet
- Applicant: Ulrich H. von Andrian , Irina Mazo , Jean-Marc Gauguet
- Applicant Address: US MA Boston
- Assignee: The CBR Institute for Biomedical Research, Inc.
- Current Assignee: The CBR Institute for Biomedical Research, Inc.
- Current Assignee Address: US MA Boston
- Agency: Rissman Hendricks & Oliverio, LLP
- Main IPC: A61K38/12
- IPC: A61K38/12 ; A61K39/395
Abstract:
Methods for treating multiple myeloma with inhibitors of CXCR4 are described. The decreased expression of CXCR4 on multiple myeloma cells according to the invention results in decreased homing of the cells to the bone marrow and a reduction in the development of the disease. Also disclosed are pharmaceutical compositions incorporating such inhibitors for use in the therapeutic treatment of multiple myeloma. The treatment methods described herein can be used independently, or in conjunction with, other therapies for the treatment of multiple myeloma.
Public/Granted literature
- US20070003558A1 Methods for the treatment of multiple myeloma Public/Granted day:2007-01-04
Information query
IPC分类:
