Invention Grant
US07825095B2 Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
有权
用于吸入给予氨基糖苷类抗生素的方法和单位剂量配方
- Patent Title: Methods and unit dose formulations for the inhalation administration of aminoglycoside antibiotics
- Patent Title (中): 用于吸入给予氨基糖苷类抗生素的方法和单位剂量配方
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Application No.: US11923486Application Date: 2007-10-24
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Publication No.: US07825095B2Publication Date: 2010-11-02
- Inventor: Robert John Speirs , Barbara Ann Schaeffler , Peter Bruce Challoner
- Applicant: Robert John Speirs , Barbara Ann Schaeffler , Peter Bruce Challoner
- Applicant Address: US CA Emeryville
- Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee: Novartis Vaccines and Diagnostics, Inc.
- Current Assignee Address: US CA Emeryville
- Agent Cozette M McAvoy
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/175 ; A01N25/00
Abstract:
A patient suffering from an endobronchial infection is treated by administering to the patient for inhalation a dose of less than about 4.0 ml of a nebulized aerosol formulation comprising from about 60 to about 200 mg/ml of an aminoglycoside antibiotic, such as tobramycin, in a physiologically acceptable carrier in a time period of less than about 10 minutes. Unit dose devices for storage and delivery of the aminoglycoside antibiotic formulations are also provided.
Public/Granted literature
- US20080095717A1 METHODS AND UNIT DOSE FORMULATIONS FOR THE INHALATION ADMINISTRATION OF AMINOGLYCOSIDE ANTIBIOTICS Public/Granted day:2008-04-24
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