Invention Grant
- Patent Title: N2, N4-bis-aryl-5-fluoro-2,4-pyrimidinediamines
- Patent Title (中): N 2，N 4 - 双 - 芳基-5-氟-2,4-嘧啶二亚胺
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Application No.: US11539101Application Date: 2006-10-05
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Publication No.: US07825116B2Publication Date: 2010-11-02
- Inventor: Rajinder Singh , Ankush Argade , Donald G. Payan , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li
- Applicant: Rajinder Singh , Ankush Argade , Donald G. Payan , Jeffrey Clough , Holger Keim , Somasekhar Bhamidipati , Catherine Sylvain , Hui Li
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D403/12 ; A61K31/506
Abstract:
The present invention provides methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds, as well as methods of treating, preventing or ameliorating symptoms associated with such diseases. Specific examples of autoimmune diseases that can be treated or prevented with the compounds include rheumatoid arthritis and/or its associated symptoms, systemic lups erythematosis and/or its associated symptoms and multiple sclerosis and/or its associated symptoms.
Public/Granted literature
- US20070299095A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES WITH 2,4-PYRIMIDINEDIAMINE COMPOUNDS Public/Granted day:2007-12-27
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