Invention Grant
US07825123B2 Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
失效
可用作多巴胺D3受体调节剂的异恶唑并[4,5]吡啶-3-基 - 哌嗪衍生物
![Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors](/docs/US/2010-11-02/US07825123B2/abs.jpg.600x600.jpg)
- Patent Title: Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
- Patent Title (中): 可用作多巴胺D3受体调节剂的异恶唑并[4,5]吡啶-3-基 - 哌嗪衍生物
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Application No.: US12561497Application Date: 2009-09-17
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Publication No.: US07825123B2Publication Date: 2010-11-02
- Inventor: Luca Gobbi , Georg Jaeschke , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- Applicant: Luca Gobbi , Georg Jaeschke , Rosa Maria Rodriguez Sarmiento , Lucinda Steward
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Priority: EP08164904 20080923
- Main IPC: A61K31/424
- IPC: A61K31/424 ; C07D498/04
![Isoxazolo[4,5]pyridin-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors](/abs-image/US/2010/11/02/US07825123B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides compounds of formula I, having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use for the therapeutic and/or prophylactic treatment of cognitive disorders.
Public/Granted literature
- US20100075981A1 ISOXAZOLO[4,5]PYRIDIN-3-YL-PIPERAZIN DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS Public/Granted day:2010-03-25
Information query
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