Invention Grant
- Patent Title: Heteroaryl piperidine glycine transporter inhibitors
- Patent Title (中): 杂芳基哌啶甘氨酸转运蛋白抑制剂
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Application No.: US10593950Application Date: 2005-03-23
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Publication No.: US07825135B2Publication Date: 2010-11-02
- Inventor: Wesley Blackaby , Mark E. Duggan , David Hallett , George D. Hartman , Andrew S. Jennings , William H. Leister , Richard T. Lewis , Craig W. Lindsley , Elizabeth Naylor , Leslie J. Street , Yi Wang , David D. Wisnoski , Scott E. Wolkenberg , Zhijian Zhao
- Applicant: Wesley Blackaby , Mark E. Duggan , David Hallett , George D. Hartman , Andrew S. Jennings , William H. Leister , Richard T. Lewis , Craig W. Lindsley , Elizabeth Naylor , Leslie J. Street , Yi Wang , David D. Wisnoski , Scott E. Wolkenberg , Zhijian Zhao
- Applicant Address: GB Hertfordshire US NJ Rahway
- Assignee: Merck Sharp & Dohme Limited,Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Limited,Merck Sharp & Dohme Corp.
- Current Assignee Address: GB Hertfordshire US NJ Rahway
- Agent Gereard Devlin; Raynard Yurd
- International Application: PCT/US2005/009810 WO 20050323
- International Announcement: WO2005/094514 WO 20051013
- Main IPC: A61K31/435
- IPC: A61K31/435 ; A61K31/445
Abstract:
The present invention is directed to pyridyl, pyridazinyl, pyrimidinyl and pyrazinyl piperidine compounds that inhibit the glycine transporter GlyT1 and which are useful in the treatment of neurological and psychiatric disorders associated with glycinergic or glutamatergic neurotransmission dysfunction and diseases in which the glycine transporter GlyT1 is involved.
Public/Granted literature
- US20070254880A1 Heteroaryl Piperidine Glycine Transporter Inhibitors Public/Granted day:2007-11-01
Information query
