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US07825146B2 Sulfonamide derivative having isoxazole ring 失效
具有异恶唑环的磺酰胺衍生物

Sulfonamide derivative having isoxazole ring
Abstract:
A compound represented by the general formula (I-A): wherein R1 is hydroxy and the like; R2 is optionally substituted lower alkyl and the like; R3 is hydrogen atom and the like; R4 is optionally substituted arylene and the like; R5 is a group represented by the formula: R6 is optionally substituted aryl and the like, its optically active substance, their pharmaceutically acceptable salt, or a solvate thereof; and a metalloproteinase inhibitor containing them.
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