Invention Grant
- Patent Title: Small molecule inhibitors of botulinum neurotoxins
- Patent Title (中): 肉毒杆菌神经毒素的小分子抑制剂
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Application No.: US11464007Application Date: 2006-08-11
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Publication No.: US07825154B2Publication Date: 2010-11-02
- Inventor: Sina Bavari , Rick Gussio , James C. Burnett
- Applicant: Sina Bavari , Rick Gussio , James C. Burnett
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee: The United States of America as represented by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Elizabeth Arwine
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A01N43/38 ; A01N43/06 ; A01N43/08 ; C07D333/02
Abstract:
Disclosed herein are methods of inhibiting the activity of Botulinum neurotoxin A metalloprotease with the compounds disclosed herein. Also disclosed are methods of treating, inhibiting or preventing intoxication caused by bacteria of at least one bacterial strain in a subject, and pharmaceutical and cosmetic compositions comprising the compounds disclosed herein.
Public/Granted literature
- US20070112049A1 Small Molecule Inhibitors of Botulinum Neurotoxins Public/Granted day:2007-05-17
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