发明授权
US07825162B2 Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease
有权
二亚戊基二萜类化合物，以及包含提取物的组合物，其中包括从其中分离出来的托雷单抗或二萜二萜化合物或萜类化合物，用于预防和治疗心血管疾病
- 专利标题： Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease
- 专利标题（中）： 二亚戊基二萜类化合物，以及包含提取物的组合物，其中包括从其中分离出来的托雷单抗或二萜二萜化合物或萜类化合物，用于预防和治疗心血管疾病
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申请号： US12265088申请日： 2008-11-05
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公开(公告)号： US07825162B2公开(公告)日： 2010-11-02
- 发明人: Tae-Sook Jeong , Woo-Song Lee , Hyoung-Chin Kim , Yang-Kyu Choi , Ju-Ryoung Kim , So-Jin An , Kyoung-Ran Im , Ki-Chang Jang , Og-Sung Moon , Jun-Seock Son
- 申请人： Tae-Sook Jeong , Woo-Song Lee , Hyoung-Chin Kim , Yang-Kyu Choi , Ju-Ryoung Kim , So-Jin An , Kyoung-Ran Im , Ki-Chang Jang , Og-Sung Moon , Jun-Seock Son
- 申请人地址： KR Taijeon-Si
- 专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人地址： KR Taijeon-Si
- 代理机构： Lucas & Mercanti, LLP
- 优先权： KR10-2004-0014236 20040303; KR10-2004-0089372 20041104; KR10-2004-0112140 20041224
- 主分类号： A61K31/17
- IPC分类号： A61K31/17
摘要：
A method for treating cardiovascular disease, including hyperlipidemia and atherosclerosis, using abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera as an effective ingredient. The abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera not only excellently inhibits oxidation of low-density lipoprotein (LDL), but also effectively inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity.
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