Invention Grant
US07825162B2 Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease
有权
二亚戊基二萜类化合物，以及包含提取物的组合物，其中包括从其中分离出来的托雷单抗或二萜二萜化合物或萜类化合物，用于预防和治疗心血管疾病
- Patent Title: Abietane diterpenoid compound, and composition comprising extract of torreya nucifera, or abietane diterpenoid compounds or terpenoid compounds isolated from them for prevention and treatment of cardiovascular disease
- Patent Title (中): 二亚戊基二萜类化合物，以及包含提取物的组合物，其中包括从其中分离出来的托雷单抗或二萜二萜化合物或萜类化合物，用于预防和治疗心血管疾病
-
Application No.: US12265088Application Date: 2008-11-05
-
Publication No.: US07825162B2Publication Date: 2010-11-02
- Inventor: Tae-Sook Jeong , Woo-Song Lee , Hyoung-Chin Kim , Yang-Kyu Choi , Ju-Ryoung Kim , So-Jin An , Kyoung-Ran Im , Ki-Chang Jang , Og-Sung Moon , Jun-Seock Son
- Applicant: Tae-Sook Jeong , Woo-Song Lee , Hyoung-Chin Kim , Yang-Kyu Choi , Ju-Ryoung Kim , So-Jin An , Kyoung-Ran Im , Ki-Chang Jang , Og-Sung Moon , Jun-Seock Son
- Applicant Address: KR Taijeon-Si
- Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee: Korea Research Institute of Bioscience and Biotechnology
- Current Assignee Address: KR Taijeon-Si
- Agency: Lucas & Mercanti, LLP
- Priority: KR10-2004-0014236 20040303; KR10-2004-0089372 20041104; KR10-2004-0112140 20041224
- Main IPC: A61K31/17
- IPC: A61K31/17
Abstract:
A method for treating cardiovascular disease, including hyperlipidemia and atherosclerosis, using abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera as an effective ingredient. The abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera not only excellently inhibits oxidation of low-density lipoprotein (LDL), but also effectively inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity.
Public/Granted literature
Information query
