Invention Grant
- Patent Title: Optimizing expression of active Botulinum Toxin type E
- Patent Title (中): 优化活性肉毒杆菌毒素E型的表达
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Application No.: US11568834Application Date: 2005-06-09
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Publication No.: US07825233B2Publication Date: 2010-11-02
- Inventor: Lance E. Steward , Marcella A. Gilmore , Ester G. Fernandez-Salas , Shengwen Li , Ronald G. Miller , Kei Roger Aoki
- Applicant: Lance E. Steward , Marcella A. Gilmore , Ester G. Fernandez-Salas , Shengwen Li , Ronald G. Miller , Kei Roger Aoki
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Dean G. Stathakis; Debra Condino
- International Application: PCT/US2005/020578 WO 20050609
- International Announcement: WO2005/011966 WO 20060202
- Main IPC: C12N5/06
- IPC: C12N5/06 ; C07H21/04
Abstract:
Nucleic acid molecules that comprise modified open reading frames providing increased expression of the encoded active BoNT/E in a heterologous cell, expression constructs and cells comprising such nucleic acid molecules and methods useful for expressing the encoding active BoNT/E from such nucleic acid molecules, expression constructs and cells.
Public/Granted literature
- US20080138893A1 Optimizing Expression Of Active BotulinumToxin Type E Public/Granted day:2008-06-12
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