Invention Grant
- Patent Title: Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
- Patent Title (中): 用于合成烷基喹啉和烷基喹唑啉激酶调节剂的中间体及其相关合成方法
-
Application No.: US11422352Application Date: 2006-06-06
-
Publication No.: US07825244B2Publication Date: 2010-11-02
- Inventor: Nand Baindur , Michael David Gaul , Kevin Douglas Kreutter , Guozhang Xu
- Applicant: Nand Baindur , Michael David Gaul , Kevin Douglas Kreutter , Guozhang Xu
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Main IPC: C07D239/88
- IPC: C07D239/88 ; C07D239/94 ; C07D215/12 ; C07D215/14
Abstract:
The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: wherein R1, R2, R99, and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.
Public/Granted literature
Information query
