Invention Grant
- Patent Title: Heteroaromatic quinoline compounds
- Patent Title (中): 杂芳族喹啉化合物
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Application No.: US12037964Application Date: 2008-02-27
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Publication No.: US07825254B2Publication Date: 2010-11-02
- Inventor: Patrick R. Verhoest , Christopher J. Helal , Dennis J. Hoover , John M. Humphrey
- Applicant: Patrick R. Verhoest , Christopher J. Helal , Dennis J. Hoover , John M. Humphrey
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Jennifer A. Kispert; Garth C. Butterfield
- Main IPC: C07D215/12
- IPC: C07D215/12 ; A61K31/47
Abstract:
The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
Public/Granted literature
- US20080214607A1 HETEROAROMATIC QUINOLINE COMPOUNDS Public/Granted day:2008-09-04
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