Invention Grant
US07825263B2 Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive
失效
卡维地洛和其他β受体阻滞剂的硝基氧化酶作为抗高血压药物
- Patent Title: Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive
- Patent Title (中): 卡维地洛和其他β受体阻滞剂的硝基氧化酶作为抗高血压药物
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Application No.: US10577912Application Date: 2004-12-01
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Publication No.: US07825263B2Publication Date: 2010-11-02
- Inventor: Piero Del Soldato , Francesca Benedini , Ennio Ongini
- Applicant: Piero Del Soldato , Francesca Benedini , Ennio Ongini
- Applicant Address: FR Sophia Antipolis - Valbonne
- Assignee: Nicox S.A.
- Current Assignee: Nicox S.A.
- Current Assignee Address: FR Sophia Antipolis - Valbonne
- Agency: Arent Fox LLP
- Priority: EP03104484 20031202
- International Application: PCT/EP2004/013683 WO 20041201
- International Announcement: WO2005/053685 WO 20050616
- Main IPC: C07D209/82
- IPC: C07D209/82 ; A61K31/403
Abstract:
The present invention relates to β-adrenergic blockers nitrooxyderivatives of general formula (I): A-(Y—ONO2)s and enantiomers and diastereoisomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them and their use for the treatment of hypertension, cardiovascular diseases, glaucoma, migraine headache and vascular diseases.
Public/Granted literature
- US20070072854A1 Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive Public/Granted day:2007-03-29
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