Invention Grant
- Patent Title: Fused ring dicationic anti-protozoan agents and their prodrugs
- Patent Title (中): 融合环双阳离子抗原生动物及其前药
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Application No.: US10992607Application Date: 2004-11-18
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Publication No.: US07825279B2Publication Date: 2010-11-02
- Inventor: David W. Boykin , Richard R. Tidwell , W. David Wilson , Reto Brun , Reem K. Arafa , Chad E. Stephens
- Applicant: David W. Boykin , Richard R. Tidwell , W. David Wilson , Reto Brun , Reem K. Arafa , Chad E. Stephens
- Applicant Address: US NC Chapel Hill US GA Atlanta
- Assignee: The University of North Carolina at Chapel Hill,Georgia State University Research Foundation, Inc.
- Current Assignee: The University of North Carolina at Chapel Hill,Georgia State University Research Foundation, Inc.
- Current Assignee Address: US NC Chapel Hill US GA Atlanta
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- Main IPC: C07C279/18
- IPC: C07C279/18 ; C07D219/12 ; C07D213/06 ; A61K31/155 ; A61K31/235 ; A61K31/24 ; A61K31/44

Abstract:
Novel fused ring dicationic anti-protozoan compounds. Representative protozoan species include but are not limited to Trypanosoma brucei rhodesiense (T.b.r.) and Plasmodium falciparum. Prodrugs of these compounds can be used as an oral treatment for malaria and human African trypanosomiasis.
Public/Granted literature
- US20050165044A1 Fused ring dicationic anti-protozoan agents and their prodrugs Public/Granted day:2005-07-28
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