A transmission circuit and related method are disclosed. A transmitter in the transmission circuit has CMOS transistors as driving units for responding an input signal to drive an output signal at an output node, and each driving unit has a corresponding charge unit formed by a capacitor-connected MOS of a same type as that of the corresponding driving unit. Each charge unit is controlled by an auxiliary signal inverse to the input signal. When a level transition occurs in the input signal, the charge unit can compensate charge injection and clock feed-through caused by the driving unit at the output node, and form peaks for pre-emphasis. In this way, a better transmission property can be realized by using a simpler and low-power circuit design.