Optical devices, systems, and methods can produce and/or measure cylindrical (as well as spherical) lens shapes throughout a range of both powers and cylindrical axes. Fluid focus lenses employ electrical potentials to vary the shape of a fluid/fluid interface between two immiscible fluids having differing indices of refractions by controlling localized angles between the interface and a surrounding container wall. Spherical power, cylindrical power, and cylindrical access alignment may be varied with no moving parts (other than the fluids).