发明授权
US07829076B2 Method of using interferon-like potein ZCYTO20 (IL-28A) or ZCYTO22(IL-28B) to treat hepatitis B
有权
使用干扰素样potein ZCYTO20（IL-28A）或ZCYTO22（IL-28B）治疗乙型肝炎的方法
- 专利标题： Method of using interferon-like potein ZCYTO20 (IL-28A) or ZCYTO22(IL-28B) to treat hepatitis B
- 专利标题（中）： 使用干扰素样potein ZCYTO20（IL-28A）或ZCYTO22（IL-28B）治疗乙型肝炎的方法
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申请号： US12630571申请日： 2009-12-03
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公开(公告)号： US07829076B2公开(公告)日： 2010-11-09
- 发明人: Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- 申请人： Paul O. Sheppard , Brian A. Fox , Kevin M. Klucher , David W. Taft , Wayne Kindsvogel
- 申请人地址： US TN Nashville
- 专利权人： ZymoGenetics, LLC
- 当前专利权人： ZymoGenetics, LLC
- 当前专利权人地址： US TN Nashville
- 代理商 Brian J. Walsh
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61K38/00 ; A61K38/21 ; C07K14/00
摘要：
The present invention relates to polynucleotide and polypeptide molecules for zcyto20, zcyto21, zcyto22, zycto24, and zcyto25 proteins which are most closely related to interferon-α at the amino acid sequence level. The receptor for this protein family is a class II cytokine receptor. The present invention includes methods of reducing viral infections and increasing monocyte counts. The present invention also includes antibodies to the zcyto20 polypeptides, and methods of producing the polynucleotides and polypeptides.
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