发明授权
- 专利标题: Cleavage of nucleic acids
- 专利标题(中): 切断核酸
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申请号: US12476912申请日: 2009-06-02
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公开(公告)号: US07829314B2公开(公告)日: 2010-11-09
- 发明人: James R. Prudent , Jeff G. Hall , Victor I. Lyamichev , Mary Ann D. Brow , James E. Dahlberg
- 申请人: James R. Prudent , Jeff G. Hall , Victor I. Lyamichev , Mary Ann D. Brow , James E. Dahlberg
- 申请人地址: US WI Madison
- 专利权人: Third Wave Technologies, Inc.
- 当前专利权人: Third Wave Technologies, Inc.
- 当前专利权人地址: US WI Madison
- 代理机构: Casimir Jones, S.C.
- 主分类号: C12P19/34
- IPC分类号: C12P19/34
摘要:
The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
公开/授权文献
- US20090305283A1 CLEAVAGE OF NUCLEIC ACIDS 公开/授权日:2009-12-10
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