发明授权
- 专利标题: Recovery and recycling of chiral tartaric acid resolving agents
- 专利标题(中): 手性酒石酸分解剂的回收和再循环
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申请号: US10495359申请日: 2002-11-08
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公开(公告)号: US07838700B2公开(公告)日: 2010-11-23
- 发明人: Steve Martin , Daniele Piergentili
- 申请人: Steve Martin , Daniele Piergentili
- 申请人地址: GB Cramlington
- 专利权人: Aesica Pharmaceuticals
- 当前专利权人: Aesica Pharmaceuticals
- 当前专利权人地址: GB Cramlington
- 代理机构: Novak Druce + Quigg LLP
- 优先权: GB0127346.5 20011114
- 国际申请: PCT/EP02/12494 WO 20021108
- 国际公布: WO03/042132 WO 20030522
- 主分类号: C07B57/00
- IPC分类号: C07B57/00 ; C07C51/00
摘要:
A process for the recovery of substituted tartaric acid resolving agents from resolution process liquors comprising organic solvents, wherein the substituted tartaric acid derivatives are neutralised by adding a base, extracted into an aqueous phase and crystallized from the aqueous phase by addition of a mineral acid in the presence of an organic solvent.
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