Disclosed herein are a liquid crystal display device, in which a bi-directional internal gate drive circuit is used to cut the number of data lines in half, and a method of driving such liquid crystal display devices. The liquid crystal device includes a pixel array having a plurality of pixels on a lower substrate. The pixels are configured such that two pixels horizontally adjacent to each other are paired to share the same data line. First and second gate drive circuits are housed in the left and right sides of the lower substrate so as to be independently operated in the left and right side of the pixel array. The first gate drive circuit is formed of first to nth odd shift registers, and the second gate drive circuit is formed of first to nth even shift registers.