Invention Grant
US07842292B2 Methods for treating B-cell malignancies using a TACI-Ig fusion molecule
有权
使用TACI-Ig融合分子治疗B细胞恶性肿瘤的方法
- Patent Title: Methods for treating B-cell malignancies using a TACI-Ig fusion molecule
- Patent Title (中): 使用TACI-Ig融合分子治疗B细胞恶性肿瘤的方法
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Application No.: US11502134Application Date: 2006-08-09
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Publication No.: US07842292B2Publication Date: 2010-11-30
- Inventor: Herve Broly , Arnaud Ythier , Eric Sievers , Sharon J. Busby , Jan Öhrström , Ivan Nestorov , Stephen M. Ansell
- Applicant: Herve Broly , Arnaud Ythier , Eric Sievers , Sharon J. Busby , Jan Öhrström , Ivan Nestorov , Stephen M. Ansell
- Applicant Address: CH US WA Seattle US MN Rochester
- Assignee: Ares Trading S.A.,Zymogenetics, Inc.,Mayo Foundation for Medical Education and Research
- Current Assignee: Ares Trading S.A.,Zymogenetics, Inc.,Mayo Foundation for Medical Education and Research
- Current Assignee Address: CH US WA Seattle US MN Rochester
- Agency: Howrey LLP
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention provides methods and compositions for treatment of B-cell malignancies, including non-Hodgkin's lymphoma, comprising administering to a patient in need of the treatment a TACI-Ig fusion molecule in amount sufficient to suppress proliferation-inducing functions of BlyS and APRIL.
Public/Granted literature
- US20070071760A1 Methods for treating B-cell malignancies using a TACI-Ig fusion molecule Public/Granted day:2007-03-29
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