发明授权
- 专利标题： Heterocyclic sulfonamide inhibitors of beta amyloid production
- 专利标题（中）： β-淀粉样蛋白生成的杂环磺酰胺抑制剂
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申请号： US12576513申请日： 2009-10-09
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公开(公告)号： US07842718B2公开(公告)日： 2010-11-30
- 发明人: Anthony Frank Kreft , Derek Cecil Cole , Kevin R. Woller , Joseph Raymond Stock , George Diamantidis , Dennis Michael Kubrak , Kristina Martha Kutterer , William J. Moore , David S. Casebier
- 申请人： Anthony Frank Kreft , Derek Cecil Cole , Kevin R. Woller , Joseph Raymond Stock , George Diamantidis , Dennis Michael Kubrak , Kristina Martha Kutterer , William J. Moore , David S. Casebier
- 申请人地址： US NJ Madison US MA Woburn
- 专利权人： Wyeth LLC,ArQule, Inc.
- 当前专利权人： Wyeth LLC,ArQule, Inc.
- 当前专利权人地址： US NJ Madison US MA Woburn
- 代理机构： Howson & Howson LLP
- 代理商 Martha G. Munchhof
- 主分类号： A61K31/381
- IPC分类号： A61K31/381 ; C07D333/34
摘要：
Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.
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