Invention Grant
US07848890B2 Method and system for predicting gene pathway using gene expression pattern data and protein interaction data
失效
使用基因表达模式数据和蛋白质相互作用数据预测基因途径的方法和系统
- Patent Title: Method and system for predicting gene pathway using gene expression pattern data and protein interaction data
- Patent Title (中): 使用基因表达模式数据和蛋白质相互作用数据预测基因途径的方法和系统
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Application No.: US11297008Application Date: 2005-12-07
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Publication No.: US07848890B2Publication Date: 2010-12-07
- Inventor: Ho Youl Jung , Mi Young Shin , Sun Hee Park
- Applicant: Ho Youl Jung , Mi Young Shin , Sun Hee Park
- Applicant Address: KR Daejeon
- Assignee: Electronics and Telecommunications Research Institute
- Current Assignee: Electronics and Telecommunications Research Institute
- Current Assignee Address: KR Daejeon
- Agency: Blakely, Sokoloff, Taylor & Zafman LLP
- Priority: KR10-2004-0102913 20041208; KR10-2005-0068784 20050728
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Provided are a method and system for predicting pathways of genes that serve the same biological purpose using gene expression pattern data and protein interaction data. The method of predicting a gene pathway includes: a first step of generating partial pathways from gene expression pattern data by using a pathway extraction algorithm, and matching the partial pathways to express them as a graph; a second step of generating partial pathways from protein interaction data by using a pathway extraction algorithm, and matching the partial pathways to express them as a graph; and a third step of combining a graph made in the first step and a graph made in the second step by using a graph matching algorithm to make a combined graph.
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