发明授权
- 专利标题: Alkylated semi-synthetic glycosaminoglycosan ethers, and methods of making and using thereof
- 专利标题(中): 烷基化半合成糖胺聚糖醚,及其制备和使用方法
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申请号: US12870763申请日: 2010-08-27
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公开(公告)号: US07855187B1公开(公告)日: 2010-12-21
- 发明人: Glenn D. Prestwich , Jianxing Zhang , Thomas P. Kennedy , Narayanam V. Rao , Xiaoyu Xu
- 申请人: Glenn D. Prestwich , Jianxing Zhang , Thomas P. Kennedy , Narayanam V. Rao , Xiaoyu Xu
- 申请人地址: US UT Salt Lake City
- 专利权人: University of Utah Research Foundation
- 当前专利权人: University of Utah Research Foundation
- 当前专利权人地址: US UT Salt Lake City
- 代理商 Ted W Whitlock
- 主分类号: A61K31/715
- IPC分类号: A61K31/715
摘要:
Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders.
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