发明授权
US07858388B2 MS based peptide and protein sequencing via reactions of lysine residues with peroxycarbonate compounds
失效
基于MS的肽和蛋白质测序通过赖氨酸残基与过氧碳酸酯化合物的反应
- 专利标题: MS based peptide and protein sequencing via reactions of lysine residues with peroxycarbonate compounds
- 专利标题(中): 基于MS的肽和蛋白质测序通过赖氨酸残基与过氧碳酸酯化合物的反应
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申请号: US10576218申请日: 2004-10-14
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公开(公告)号: US07858388B2公开(公告)日: 2010-12-28
- 发明人: Ned A. Porter , Douglas S. Masterson , Huiyong Yin , Richard M. Caprioli , Jeremy L. Norris
- 申请人: Ned A. Porter , Douglas S. Masterson , Huiyong Yin , Richard M. Caprioli , Jeremy L. Norris
- 申请人地址: US TN Nashville
- 专利权人: Vanderbilt University
- 当前专利权人: Vanderbilt University
- 当前专利权人地址: US TN Nashville
- 代理机构: Stites & Harbison PLLC
- 代理商 Richard S. Myers, Jr.
- 国际申请: PCT/US2004/033951 WO 20041014
- 国际公布: WO2005/037857 WO 20050428
- 主分类号: G01N24/00
- IPC分类号: G01N24/00 ; G01N33/00
摘要:
A method of modifying protein samples that comprises combining the sample with a peroxycarbonate solution and inserting the sample into a mass spectrometer. The present invention also includes methods of N-terminus characterization.
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