Invention Grant
- Patent Title: IRE-1α inhibitors
- Patent Title (中): IRE-1α抑制剂
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Application No.: US12135571Application Date: 2008-06-09
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Publication No.: US07858666B2Publication Date: 2010-12-28
- Inventor: John B. Patterson , David G. Lonergan , Gary A. Flynn , Qingping Zeng , Peter V. Pallai
- Applicant: John B. Patterson , David G. Lonergan , Gary A. Flynn , Qingping Zeng , Peter V. Pallai
- Applicant Address: US CA Valencia
- Assignee: MannKind Corporation
- Current Assignee: MannKind Corporation
- Current Assignee Address: US CA Valencia
- Agency: Banner & Witcoff, Ltd.
- Main IPC: A01N35/00
- IPC: A01N35/00 ; A61K31/00 ; C07C47/00
Abstract:
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
Public/Granted literature
- US20090186893A1 IRE-1alpha INHIBITORS Public/Granted day:2009-07-23
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