发明授权
- 专利标题： Lactams and uses thereof
- 专利标题（中）： 内酰胺及其用途
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申请号： US12359465申请日： 2009-01-26
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公开(公告)号： US07858776B2公开(公告)日： 2010-12-28
- 发明人: Bruce Thomas Dembofsky , Robert Jacobs , Cyrus Ohnmacht
- 申请人： Bruce Thomas Dembofsky , Robert Jacobs , Cyrus Ohnmacht
- 申请人地址： SE Sodertalje
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 当前专利权人地址： SE Sodertalje
- 优先权： SE0202929 20021003; SE0203829 20021218
- 主分类号： C07D223/16
- IPC分类号： C07D223/16
摘要：
Compounds having the formula (I) pharmaceutical compositions containing them and their methods of use for the treatment of neurological disorders related to amyloid β protein production and neurological disorders such as Alzheimer's disease. These compounds inhibit γ secretase and thereby inhibit the production of amyloid β protein, thereby acting to prevent the formation of neurological deposits of amyloid protein.
公开/授权文献
- US20100160627A1 NOVEL LACTAMS AND USES THEREOF 公开/授权日：2010-06-24