发明授权
- 专利标题: Pyrimidines and pyrazines useful as modulators of ion channels
- 专利标题(中): 嘧啶和吡嗪可用作离子通道的调节剂
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申请号: US11418163申请日: 2006-05-04
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公开(公告)号: US07858786B2公开(公告)日: 2010-12-28
- 发明人: Dean Wilson , Andreas Termin , Dewey Fanning , Paul Krenitsky , Pramod Joshi , Urvi Sheth
- 申请人: Dean Wilson , Andreas Termin , Dewey Fanning , Paul Krenitsky , Pramod Joshi , Urvi Sheth
- 申请人地址: US MA Cambridge
- 专利权人: Vertex Pharmaceuticals Incoropated
- 当前专利权人: Vertex Pharmaceuticals Incoropated
- 当前专利权人地址: US MA Cambridge
- 代理商 Michael C. Badia
- 主分类号: C07D403/04
- IPC分类号: C07D403/04 ; C07D401/04 ; A61K31/506 ; A61K31/496 ; A61P19/02 ; A61P25/02 ; A61P25/06
摘要:
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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