A patient bed includes a patient support, with a headboard, a footboard, and a plurality of side rails. One or more surfaces of the side rails or of the headboard or of the footboard includes a gap and a sealing cover for sealing the gap to facilitate cleaning and disinfection of the patient bed. For example, the cover may comprise a membrane that is applied to the surface, for example, by an adhesive. The adhesive may be releasable so that the membrane may be removed for replacement or to provide access to the gap for example, where the gap is formed between a control interface that is located in the surface.