发明授权
US07863021B2 Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
有权
与类风湿关节炎相关的遗传多态性,检测方法及其应用
- 专利标题: Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
- 专利标题(中): 与类风湿关节炎相关的遗传多态性,检测方法及其应用
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申请号: US12231877申请日: 2008-09-04
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公开(公告)号: US07863021B2公开(公告)日: 2011-01-04
- 发明人: Steven J. Schrodi , Ann B. Bogovich
- 申请人: Steven J. Schrodi , Ann B. Bogovich
- 申请人地址: US CA Alameda
- 专利权人: Celera Corporation
- 当前专利权人: Celera Corporation
- 当前专利权人地址: US CA Alameda
- 主分类号: C12P19/24
- IPC分类号: C12P19/24 ; C12Q1/68 ; C07H21/02 ; C07H21/04
摘要:
The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
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